Recombinant human BEND6, His-tagged

TypeName:
Business Offer
Request Date:
2017/04/18
Country:
United States
Summary:
Recombinant human BEND6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Description:
BEND6, as known as BEN domain-containing protein 6, is a neural BEN-solo factor that shares many functional attributes with Drosophila Insensitive, a co-repressor for the Drosophila CSL factor. This protein binds the mammalian CSL protein CBF1 and antagonizes Notch-dependent target activation. In addition, its association with Notch- and CBF1-regulated enhancers is promoted by CBF1 and antagonized by activated Notch. In utero electroporation experiments showed that ectopic BEND6 inhibited Notch-mediated self-renewal of neocortical neural stem cells and promoted neurogenesis.
Advantages:
Comments:
http://www.creativebiomart.net/description_387441_12.htm
RequestId:
98
Name:
Caroline Green
Telphone:
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