DBCO-PEG4-Ahx-DM1

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Name
DBCO-PEG4-Ahx-DM1
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Note
Linker-Toxin SET, This set is made by DM1 conjugated to DBCO-PEG4-Ahx linker. DM1 belongs to Maytansinoids which are a group of cytotoxins structurally similar to rifamycin, geldanamycin, and ansatrienin. Maytansinoids can bind to tubulin at or near the vinblastine-binding site, which interfere the formation of microtubules and depolymerize already formed microtubules, inducing mitotic arrest in the intoxicated cells. https://www.creative-biolabs.com/adc/classify-drug-linker-complexes-8.htm
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