Cas9 Stable Cell Lines

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Cas9 Stable Cell Lines
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Creative Biogene has developed a series of Cas9 expressing stable cell lines. Cas9 encoding gene is stably integrated into either random site, or AAVS1 safe harbor site of human genome, or ROSA26 safe harbor site of mouse genome. Apart from HEK293 and HeLa cells, we have achieved Cas9 stable expression in several types of cancer cells which makes it convenient for scientists to study related gene functions of certain cancers. For consistent, high-level and more stable expression of Cas9, monoclonal cells are isolated. The activity of Cas9 in each constructed stable cell line is functionally validated by the means of T7 Endonuclease I assay.
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