Fructosamine Assay Kit (Colorimetric)

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United States

Fructosamines are stable glycated proteins that are formed by a non-enzymatic reaction between glucose and serum proteins (usually albumin). Elevated concentrations of fructosamine can be found in serum samples of diabetic patients and its detection can be used to assess the glycemic status of diabetics. The half-life of albumin is shorter when compared to hemoglobin (t1/2= 20 days vs. 50 days respectively). Thus, fructosamine levels reflect the efficacy of treatment in diabetic patients during short-term periods, and provide earlier and more sensitive detection for diabetes than many other carbohydrate tests. Fructosamine Assay Kit is a microplate-based colorimetric assay for the direct determination of fructosamine levels in serum. The assay is based on the ability of fructosamine to reduce nitroblue tetrazolium (NBT), forming a colored end-product (purple) under alkaline conditions. The formation rate of formazan is proportional to the concentration of fructosamine in samples and th

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