Recombinant Human CTLA4, His-tagged, Biotinylated

TypeName:
Business Offer
Request Date:
2017/05/06
Country:
United States
Summary:
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Description:
http://www.creativebiomart.net/description_391713_12.htm
Advantages:
Comments:
RequestId:
137
Name:
Caroline Green
Telphone:
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