Product & Services Detail

This ADC product is comprised of an anti-human IgG Fc specific polyclonal antibody conjugated via a cleavable linker to PNU-159682. The antibody portion is a secondary antibody and the drug portion, PNU-159682, is a cytotoxic small molecule which binds to DNA, causes DNA damage. This product displays no obvious toxicity without a primary antibody and can be a quite efficient and economical alternative to pre-screening human monoclonal antibodies as ADC candidates.


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